Registry Editor got some facelift in recent Windows 10 Build. Not only does it have a new Address Bar where you can type in a registry key path to jump directly to it, but it also has a hidden feature that lets you change the default font to the one you like to see.
All you need is to make a registry tweak.
Open Registry Editor (regedit.exe) and navigate to the following location:
HKEY_Local_Machine\Software\Microsoft\Windows\CurrentVersion
Create a new Key called Regedit under CurrentVersion, then create a new String value called FontFace.
Now, double-click FontFace and enter the name of the font you want to use, such as Segoe UI, Segoe UI Light, Calibri, Georgia, Harrington, etc.. You can set and use any font you want, as long as they are installed and available to use in the system.
Close and re-open Registry Editor to see how the new font looks like in the editor.