Win+S is a system designed keyboard shortcut to open Cortana search window in Windows 10. Is it possible to disable it so it can remain un-used for other programs later on?
Here is a simple registry tweak that you can use to disable any specific Win keyboard combinations in Windows 7, 8, and 10.
Open Registry Editor and navigate to the following registry key location.
Right-click the empty space on the right pane, choose New > String Value.
Name the new string as “DisabledHotkeys“, and set its value as “S“, meaning to disable any keyboard shortcut that uses the combination of Win key and the disabled character in the String Value, such as Win+S, Win+Shift+S, etc.
If you would like to disable another win keys, i.e. Win+C, you can add the letter to the String Value like “S,C”.
Either reboot your computer or restart Explorer process from Task Manager, the keyboard shortcuts specified in the registry will become unavailable in Windows.
What if I want to disable all Windows Key Hotkeys?
Open Group Policy Editor, navigate to the following location:
User Configuration > Administrative Templates > Windows Components > File Explorer
Double-click a policy called “Turn off Windows Key hotkeys“, select Enable and OK to save it.
Again, restart your computer or Explorer process to apply the change. Once done, all Windows key related keyboard shortcuts will be disable.